Deep Learning | Drug Discovery | Computational Biology
Associate Professor at the Department of Informatics Engineering, University of Coimbra, and Researcher at CISUC. I lead research efforts in applying AI to solve complex biological challenges, specifically in molecular generation and genomic analysis.
AI model for Enhancing kinase-inhibitor activity and selectivity. Joint work with Liu Huanxiang from MPU
Our work was promoted by the main Portuguese media, such as Jornal Público, Jornal Observador and Jornal Expresso.
CHAFT, VIBES and IA4FARMA projects were funded. more than 800k euros.
Deep Learning models for prediction of Protein-Drug interactions.
Language models for de novo generation of SMILES of molecules with desired properties.
Analysis of genetic variants to find those associated with a specific trait or disease.
Computational models of how genetic profiles influences the effect of drugs.
ColaboratorInvited Adjunt Professor at Polytechnic Institute of Santarém
ColaboratorResercher at Center for Neuroscience and Cell Biology, University of Coimbra
ColaboratorResearcher at Multidisciplinary Institute of Ageing, University of Coimbra
PhD student AI-Driven Knowledge Graphs: Automating Adaptive Rule Discovery for Intelligent Systems
PhD studentClassifying Functional Impairments in Foot Clinic Patients using Plantar Pressure Distributions
PhD studentMachine Learning Models for Predicting Biodegradability in Bio-Based Polyesters
PhD studentTracking clinical progression in first-episode psychosis: a biomarker-based multiomics approach
PhD studentMulti-agent framework for target-conditioned drug discovery.
PhD studentKownledge Graph for improved gene disease association
- Edgar Vicente, Master in Biomedical Engineering, UC - Mariana Morais, Master in Biomedical Engineering, UC - Guilherme Henriques, Master in Computational Biology, UC
- Edgar Coelho, former PhD student, Lead Data Scientist at MarketerHire - Fernanda Correia, former PhD student, Adjunt Professor at ISEP, IPC - António Cruz, former PhD student, Researcher at CISUC, UC - Nelson Monteiro, former PhD student, Data Scientist at Orbis Medicines - Tiago Pereira, former PhD student, Researcher at CNC, UC - Daniel Martins, former PhD student, Researcher at MIA, UC - Luis Torres, former PhD student, Artificial Intelligence Scientist at Sanofi - Anuschka da Silva Spínola, former PhD student, Researcher at CNC, UC - Fabiano Papaiz, Professor IFRN, Brasil - Yanan Tian, former PhD student, Researcher - Jianxiu Cai, former PhD student, Researcher
